You most likely have not heard a lot about gamma linolenic acid (GLA) deficiency, however it’s an excellent widespread fatty acid deficiency (I discover it in about 90% of my shoppers) that has big ramifications in your mobile well being and irritation standing. When it comes up in mainstream information, it is sometimes being touted for its pores and skin, hair and nail perks.


Frequent indicators of GLA deficiency will be imprecise, however embrace:

  • irritation
  • dry hair
  • pores and skin points
  • bumps on the again of your arms
  • cracked fingertips
  • undesirable gene expression
  • elevated physique fats

GLA Standing Determinants 

GLA is a potent anti-inflammatory omega-6 fatty acid that’s synthesized within the physique from linolenic acid (LA). Linolenic acid is discovered abundantly in omega-6 fatty acids like safflower, sunflower, sesame, corn, and cottonseed oils, which there isn’t a scarcity of in the usual American food plan.

If the precursor to GLA is considerable in most individuals’s food plan, why is GLA deficiency so rampant? 

All of it comes all the way down to conversion modulators in addition to your normal well being.

You see, there are particular modulators that assist the conversion of LA into GLA by way of the enzyme delta-6-desaturase. These embrace:

  • Zinc
  • B6
  • B3
  • Magnesium
  • Vitamin C
  • Vitamin E

In case your physique’s poor in a few of these, your GLA conversion standing will possible be impaired.

After which there are additionally modulators that block or scale back the conversion of LA into GLA. They embrace:

  • Age
  • Insulin
  • Espresso
  • Alcohol
  • Trans fat

In order you may see, bettering your GLA standing naturally requires a full body nutrition approach, though there are additionally shortcuts…

Sources of Preformed GLA

The most important shortcut to skipping any conversion points (which ought to be addressed as nicely) is taking preformed GLA.

Sources of preformed GLA embrace [1,2,3,4]:

  • leafy greens
  • hempseed
  • oats
  • spirulina
  • breastmilk (supply for infants)
  • borage oil (20-27% GLA)
  • night primrose oil (7-14% GLA)
  • black present seed oil (15-20% GLA)


The perks of GLA sufficiency are considerable, so take be aware under of what optimizing your ranges may imply for you:

GLA can have the next affect:

  • Anti-inflammatory, antithrombotic, antiproliferative (inhibit cell progress in tumor cells), lipid-lowering potential: “GLA, by way of conversion to PGE1, displays anti-inflammatory, antithrombotic, antiproliferative, and lipid-lowering potential. It additionally enhances easy muscle leisure and vasodilation. As well as, EFAs together with GLA are vital constituents of membrane phospholipids, together with the mitochondrial membrane, the place they improve the integrity and the fluidity of the membrane” [1]
  • Physique fats mass discount: A examine from 2000 linked GLA to decreasing physique fats accumulation. “It was advised that dietary gamma-linolenic acid attenuates physique fats accumulation by the rise in gene expressions of uncoupling protein 1 in brown adipose tissue. A rise in hepatic peroxisomal fatty acid oxidation may additionally contribute to the physiological exercise of gamma-linolenic acid in lowering physique fats mass.” [3]

GLA has additionally been studied for plenty of scientific purposes with promising outcomes for: [1]

  • Rheumatoid Arthritis
  • Atopic Eczema
  • Cardiovascular Illness
  • Bronchial asthma
  • Premenstrual Syndrome
  • Consideration Deficit/Hyperactivity Dysfunction
  • Most cancers
  • Dry Eye Syndrome
  • Osteoporosis


My favourite check for GLA is a simple at home blood-spot collection kit. After amassing a small drop of blood on a pattern card, you pop your pattern within the mail and get your outcomes emailed in roughly one week. I additionally created a 30 minute video coaching you may watch that can assist you perceive your outcomes and what you are able to do about it.

Gamma Linolenic Acid GLA Test Results

I sometimes check myself each 6 months or so to ensure I am conserving my fatty acid stability in test to fight mobile irritation.

Discover the easy at-home check equipment here.

A Sane Diet Method

My strategy to diet is fairly easy — ensure your physique has all of the uncooked supplies it wants (and the proper atmosphere) to assist your physique’s pure need for well being.

Give your physique what it wants (based on testing), after which get out of the best way.

Reside your life with out stressing about it.

If you happen to need assistance, yow will discover it here.


Signs of Gamma Linolenic Acid Deficiency | Butter Nutrition

Signs of Gamma Linolenic Acid Deficiency | Butter Nutrition


  5. https://www.researchgate.internet/publication/319099698_Spirulina_A_source_of_gamma-linoleic_acid_and_its_applications